Variability in JAK Inhibition Specificity & Its Clinical Implications

In this FAQ, Claudia Rivera Salas, nurse practitioner, discusses the variability in JAK enzyme inhibition among different JAK inhibitors and their potential clinical implications. She explains how each JAK inhibitor targets different JAK enzymes (JAK1, JAK2, JAK3, and TYK2), influencing immune responses and blood cell production. Dr. Rivera Salas highlights the unique effects and side effects of these inhibitors, emphasizing the need for head-to-head studies to better understand their differences.